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Brucellosis treatment based on evidence-based medicine significantly increases treatment efficacy. Brucellae are intracellular parasites that penetrate and reproduce in phagocytic and non-phagocytic cells, remaining inaccessible to the immune system in most cases. The microbe is protected by its lipopolysaccharide envelope.
#evidence-based medicine#treatment efficacy#brucellae#pathogenesis#brucellosis
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